Advanced Transfusion and Transplantation Science
30 credit level 3 module
About this course
Page last updated 14 December 2018
On successful completion of this module you will be able to:
- Critically evaluate the application of tissue science methods and techniques and illustrate their value in relevant areas of clinical practice.
- Critically evaluate the application of methods and techniques used in histocompatibility and immunogenetics and illustrate their value in relevant areas of clinical practice.
- Critically evaluate the application of stem cell science methods and techniques and illustrate their value in relevant areas of clinical practice.
Careers / Further study
This module can contibute towards:
BSc (Hons) Healthcare Science (Transfusion and Transplantation Sciences).
Core transfusion medicine
- Blood group systems - genes, antigens and antibodies
- Manual and automated techniques and technologies for ABO/D typing, serological crossmatching, red cell phenotyping, antibody screening and identification
- Overview of blood transfusion services, range of blood components/products manufactured and their applications
- Principles of pre-transfusion testing
- Normal ranges and predictive values for pathology tests used to inform transfusion support
- Aetiology and clinical features of conditions requiring transfusion support
- Overview of legislation/guidelines relevant to blood transfusion practice
- Preparation and interpretation of blood films, including blood parasites.
- Mechanisms and tests of haemostasis
- Monitoring programmes for anticoagulation therapy
- Haematinic testing and clinical applications
- Causes of haematological malignancy
- Tests for the diagnosis and management of haematological malignancy in the adult
- Minimal residual disease
- Antenatal screening tests for haemolytic disease of the foetus and newborn
- Tests of feto-maternal haemorrhage
Specialised immunology, tissue and transplantation
- Immunogenetics and the major histocompatibility complex
- Transplantation immunology and histocompatibility testing
- Tests of transplant viability and rejection
- Tests of immunosuppressive therapy
- Stem cells
- Tissue banking
- The multidisciplinary team approach to the management of tissue and organ transplantation
Learning and Teaching
You are expected to spend 72 hours on scheduled learning and 228 hours on independent learning. Theoretical material within the module will be presented to you in the form of regular lectures throughout each of the semesters in the academic year. During those times of work based learning, these lectures will be delivered online and involve a number of technological enhancements. The learning of lecture content will be reinforced through time spent in independent learning by the directed reading of recommended texts and through the use of technology enhanced learning resources that will be provided online. This online learning and engagement will be delivered through several avenues:
- Synchronous online tutorials in protected learning time where the student will contribute/attend an online activity appropriate to the content at the time at which the academic will be present online to facilitate and lead this scheduled/timetabled session. This tutorial will be themed/planned.
- Asynchronous discussions in the student's own time (or during protected time where permitted and appropriate) where they will engage/collaborate with other students on the course or in specified groups, and in which the academic is permitted to moderate where necessary, but is not expected to contribute.
- Synchronous surgery sessions timetabled for a specific time in which the academic will be available online to answer live questions via discussion boards/blogs/collaborate or to respond to questions posted/asked prior to the session.
- Interactive, online formative quizzes made available either following a particular package of knowledge exchange/learning, or in specified sessions/time periods.
- Lectures delivered online through a combination of one or more of the following: visual/audio/interactivity/personal formative assessment.
Practical classes will include simulated case-study based investigations which will allow you to develop your analytical, interpretive and data handling skills.
The remainder of the independent learning time allocated to the module should be spent preparing written assessments for submission and undertaking revision for the controlled component.
Scheduled learning includes lectures, seminars, tutorials, project supervision, demonstration, practical classes and workshops; fieldwork; external visits; work based learning; supervised time in studio/workshop.
Independent learning includes hours engaged with essential reading, case study preparation, assignment preparation and completion etc. These sessions constitute an average time per level as indicated in the table below. Scheduled sessions may vary slightly depending on the module choices you make.
There will be two weeks of contact time at UWE in two x one week blocks. Included in each block week are laboratory workshops, lectures and tutorials. The contact time will equate to approximately 12 hours per block (a total of 24 hours).
In addition to the allocated hours on campus learning, you will engage in synchronous and asynchronous online learning. This will comprise a total of approximately 48 hours of online engagement through a combination of lectures, synchronous online tutorials, synchronous and asynchronous discussions, online quizzes, and collaborative group work.
The Assessment Strategy has been designed to support and enhance the development of both subject-based and more general skills, whilst ensuring that the modules learning outcomes are attained, as described below.
The written exam will provide you with an opportunity to demonstrate your knowledge on a broad range of topics through a series of short essay questions.
Continuous assessment will be provided by the use of three x 30 minute online activities embedded in the module. These activities will require UWE login. The module leader will have full access to up-to-date data to monitor progress and marks obtained by you. Feedback at this level will also be provided online and will be by review of the tests after they have been completed and will include the correct answers (after the relevant assessment period has concluded).
The design of these online assessed activities will be varied, for example:
- Timed essay questions
- Label the structure
- Prioritisation structure
- Scenario based questions
This will provide an opportunity for you to demonstrate your ability to apply the principles of Advanced Transfusion and Transplantation Sciences to an unseen problem and/or case study and evidence your skills in approaching and interpreting it appropriately.
Formative feedback is available to you throughout the module through group discussions, and in workshops. You are provided with formative feed-forward for your exam through a revision and exam preparation session prior to the exam and through the extensive support materials supplied through Blackboard.
All work is marked in line with the Department's Generic Assessment Criteria and conforms to university policies for the setting, collection, marking and return of your work. Where an individual piece of work has specific assessment criteria, this is supplied to you when the work is set.